UMR 7025 CNRS – Enzyme and Cell Engineering

Research

Member of the theme « Biomimicry and Biomolecular Diversity »

Synthesis of nanoparticles to target gram negative bacterias and drug release.

Subject: « Molecular imprinted polymers for the vectorization and the stabilization of antimicrobial peptides : new approaches to combat antibiotic resistance » under the supervision of K. Haupt and B. Bihan-Avalle

Skills

Organic synthesis

Molecular purification and analysis : GC, RMN, liquid chromatography

Production of proteins (PCR,cell culture, electrophoresis, purification) by recombinant plasmid,.

Biocatalysis (enzypme activity assays, reactions of bioconversion)

General information

Bachelor licence degree in Biochemical and Biopharmaceutical Chemistry, Aix-Marseille University (France)

Master degree in Chemistry speciality « Chemistry of Life », Aix-Marseille University (France)
Academic research internship (Organic synthesis, Biocatalysis), Molecular Sciences Institute of Marseille (France)

PhD in Biology, Biochemistry and Cell Engineering, University of Picardie Jules Verne and University of Technology of Compiègne (France)

Personal interests

Sport, Sophrology, Music

Research

Skills

General information

Personal interests

Research

Member of the theme “Biomimicry and Biomolecular Diversity”

PhD project: “Selection and formulation of molecules to fight against Xylella fastidiosa” under the supervision of S. Octave and B. Bihan-Avalle.

Skills

Technical skills in plant biology (hydroponic plant growth), molecular biology (PCR, DNA cloning, DNA and protein analysis, MP-AES), microbiology (bacteria and yeast growth, recombinant protein production), genetics, bio-informatics (transcriptomic and genomic analysis), statistics and general lab experimentations.

Languages: French (native), English (fluent), Spanish (basic).

General information

Graduated from Ecole de Biologie Industrielle (EBI), Cergy Pontoise (France)

Specialty in Research and Application

Biology engineer diploma

Bachelor in Biochemistry and Cellular Biology,

UFR Sciences et Techniques, University of Cergy Pontoise, France

Currently PHD student in University of Technology of Compiègne (France)

Personal interests

Music, tennis, international travels

Research

Member of the theme “Biomimicry and Biomolecular Diversity”.

PhD project: “A new tool to purify methylated peptide from bacteria in order to study bacterial mechanosensing” under the supervision of S. Padiolleau and Y. Rossez.

Skills

• Technical skills: Cell culture, HPLC with fluorescence and ultraviolet detection, Gas chromatography, GC-MS, Molecular cloning, Protein expression and purification, Microbial fermentation.
• Languages: Chinese (native), English (fluent), French (basic)

General information

• 09/2012-06/2016: Bachelor degree in Biological Engineering, Huaibei Normal University (China)
• 09/2016-06/2019: Master degree in Biochemical Engineering, Zhejiang University of Technology (China)
• 12/2019-present: PhD student, UMR 7025 CNRS Enzyme and Cell Engineering, University of Technology of Compiègne (France)

Personal interests

swimming, music, reading, badminton

Research

Skills

General information

Personal interests

Research

I’m working at the interface between the two themes and working under the supervision of Pr N. d’Amelio.

Main research topics:

• Design and physicochemical characterization of antimicrobial peptides: NMR study of their interaction with the biomimetic membranes of cancer cells by NMR.
• PhD project: Design and testing of selectivity and haemolytic properties of novel antimicrobial peptides based on sequence alignments (under the supervision of Pr N. d’Amelio).

Skills

Biochemistry, microbiology, molecular biology.

General information

• Licence in pharmaceutical chemistry and biology, Veracruzana university (Mexico)
• Master in Biotechnology, Meritorious Autonomous University of Puebla (Mexico)
• PhD, Université de Picardie Jules Verne (Amiens, France)

Personal interests

Music, stand up paddle

Research

I’m member of the theme “Plant Metabolism and Bioresources” and my current research consists in studying the connection between lipid metabolism and circadian clock in Arabidopsis thaliana (under the supervision of A. Troncoso-Ponce).

Thus, Arabidopsis thaliana is cultivated under different conditions of exposure to light (constant condition or 12h in light) to determine whether lipid metabolism only depend on the diurnal rhythm or circadian rhythm too.

In the same time, lipid constituents of different circadian clock mutants are compared to their wild-type strains to identify metabolic pathways that are connected to the circadian clock.
 

Skills

Scientific skills:

Lipidomics: Connection between lipid metabolism and circadian clock in Arabidopsis thaliana, analyze of mycobacterial lipids

Metabolomics: Role of microbiota against pathogenic bacteria, comparison of different types of milk using NMR-based metabolomics.

Laboratory skills:

NMR, Mass spectrometry, extraction of metabolites and lipids, statistics (multivariate and univariate), cell culture (prokaryotic and eukaryotic), seedling culture, other skills (SDS-PAGE, Western Blot, microscopy).
 

General information

Education

• 2015-2017: Master’s degree in Metabolomics, Paul Sabatier University.
• 2012-2015: Bachelor’s degree in Biochemistry

Profesionnal experiences:

• 2015 (3 months): Engineer in Biochemistry (Lipidomics)
• 2017 (6 months): Engineer in Biochemistry (Metabolomics)
• 2017 (3 months): Engineer in Biochemistry (Metabolomics)
• Since October 2018: PhD Student in Metabolomics/lipidomics. University of Compiègne, « Génie Enzymatique et Cellulaire ».

Personal interests

Music: Violin, Sport: Basketball

Research

Member of the theme “Biomimicry and Biomolecular Diversity”.

PhD project: “Molecularly imprinted polymer nanocomposites as antibody mimics for cancer cell recognition and theranostics” under the supervision of B. Tse-Sum-Bui and K. Haupt.
Skills

• Technical skills in biology, cell engineering (cell culture, cytotoxicity assays, ELISA, etc), microscopy (epifluorescence), microfluidics, analytical methods, polymer chemistry and nanoparticles characterization.
• Languages: Spanish (native), English (fluent), French (fluent)

Roles and responsabilities

Administrative management of the MIP group.
General information

• Bachelor degree in Biochemical Engineering, Autonomous University of Aguascalientes (Mexico)
• Master degree in Biological Engineering, University of Technology of Compiègne (France)
• PhD student in University of Technology of Compiègne (France)

Personal interests 

Travel

Main publications