PhD students and Post-docs

Ranim AL AYOUBI

PhD student UPJV

Research

Member of the theme “Plant Metabolism and Bioresources”.

PhD project: Study of ethanol fermentation by yeasts of enzymatic hydrolysates of lignocellulosic substrates pretreated with ionic liquids (under the supervision of Pr C. Sarazin).

 

Skills

Enzymology, microbiology and pretreatment of lignocellulosic biomass by ionic liquids.

 

General information

  • Biochemistry licence, Lebanon
  • Applied biotechnology master, Lebanon
  • Biohemistry and enzymatic engineering PhD – in progress (Université de Picardie Jules Verne – Université Libanaise)

 

Personal interests

Swimming, hiking.

 

Morgane ADELAIDE

PhD student UPJV

Research

I’m working at the interface between the two themes “Plant Metabolism and Bioresources” and “Biomimicry and Biomolecular Recognition”. I’m under the supervision of Pr Nicola D’Amelio and Pr Catherine Sarazin.

Subject: Study of mechanism of action of new antibiotics targeting bacterial in synergies with antimicrobial peptides.

Main research topics :

  • Inside the international project NATURAL-ARSENAL (NATURAL-ARSENAL (New Antibiotics Tackling mUlti-Resistance by acting on Alternative bacteriaL tARgets in Synergy with mEmbrane-disruptiNg AntimicrobiaL peptides).

Skills

Biochemistry, molecular biology

General information

  • Bachelor degree in Biology, Molecular Biology, Microbiology, University Paul Sabatier (Toulouse, France)
  • Master degree in Structural and Functional Biochemistry, University Paul Sabatier (Toulouse, France)
  • PhD, University of Picardie Jules Verne (Amiens, France)

Claudia HERRERA LEON

PhD student UPJV
Research

I’m working at the interface between the two themes and working under the supervision of Pr N. d’Amelio.

Main research topics:

  • Design and physicochemical characterization of antimicrobial peptides: NMR study of their interaction with the biomimetic membranes of cancer cells by NMR.
  • PhD project: Design and testing of selectivity and haemolytic properties of novel antimicrobial peptides based on sequence alignments (under the supervision of Pr N. d’Amelio).

 

Skills

Biochemistry, microbiology, molecular biology.

 

General information

  • Licence in pharmaceutical chemistry and biology, Veracruzana university (Mexico)
  • Master in Biotechnology, Meritorious Autonomous University of Puebla (Mexico)
  • PhD, Université de Picardie Jules Verne (Amiens, France)

 

Personal interests

Music, stand up paddle

Salim MAKNI

PhD student UTC

Research

I’m member of the theme “Plant Metabolism and Bioresources” and my current research consists in studying the connection between lipid metabolism and circadian clock in Arabidopsis thaliana (under the supervision of A. Troncoso-Ponce).

Thus, Arabidopsis thaliana is cultivated under different conditions of exposure to light (constant condition or 12h in light) to determine whether lipid metabolism only depend on the diurnal rhythm or circadian rhythm too.

In the same time, lipid constituents of different circadian clock mutants are compared to their wild-type strains to identify metabolic pathways that are connected to the circadian clock.
 

Skills

Scientific skills:

Lipidomics: Connection between lipid metabolism and circadian clock in Arabidopsis thaliana, analyze of mycobacterial lipids

Metabolomics: Role of microbiota against pathogenic bacteria, comparison of different types of milk using NMR-based metabolomics.

Laboratory skills:

NMR, Mass spectrometry, extraction of metabolites and lipids, statistics (multivariate and univariate), cell culture (prokaryotic and eukaryotic), seedling culture, other skills (SDS-PAGE, Western Blot, microscopy).
 

General information

Education

  • 2015-2017: Master’s degree in Metabolomics, Paul Sabatier University.
  • 2012-2015: Bachelor’s degree in Biochemistry

Profesionnal experiences:

  • 2015 (3 months): Engineer in Biochemistry (Lipidomics)
  • 2017 (6 months): Engineer in Biochemistry (Metabolomics)
  • 2017 (3 months): Engineer in Biochemistry (Metabolomics)
  • Since October 2018: PhD Student in Metabolomics/lipidomics. University of Compiègne, « Génie Enzymatique et Cellulaire ».

 
 

Personal interests

Music: Violin, Sport: Basketball

 

Paulina MEDINA RANGEL

PhD student UTC

Research

Member of the theme “Biomimicry and Biomolecular Diversity”.

PhD project: “Molecularly imprinted polymer nanocomposites as plastic antibodies for cell recognition” under the supervision of B. Tse-Sum-Bui and K. Haupt.

Synthesis of biomimetic polymers for biosensing, bioimaging and biomedical applications.

 

Skills

  • Scientific writing and oral scientific communication
  • Technical skills in cellular biology (cell culture of immortalized, cancer and primary cells), microscopy (light microscopy, epifluorescence and confocal), analytical methods (spectrophotometry, fluorometry, radioactivity, enzymatic assays), polymer chemistry, nanoparticles characterization
  • Languages: Spanish (native), English (fluent), French (fluent), Italian (basic)

 

Roles and responsabilities

Student representative council

 

General information

  • Bachelor degree in Biochemical Engineering, Autonomous University of Aguascalientes (Mexico)
  • Master degree in Biological Engineering, University of Technology of Compiègne (France)
  • PhD student in University of Technology of Compiègne (France)

 

Personal interests

Music, reading.

 

Main publications

Articles

Mier A., Nestora S., Medina Rangel P., Rossez Y., Haupt K., Tse Sum Bui B. Cytocompatibility of Moleculary Imprinted Polymers for Deodorants : Evaluation on Human Keratinocytes and Axillary-Hosted Bacteria . ACS Appl. Mater. Interfaces 2019, 2 ,3439-3447    ABSTRACT: https://doi.org/10.1021/acsabm.9b00388

Medina Rangel P., Caclef S., Xu J., Panagiotopoulou M., Kovensky J., Tse Sum Bui B., Haupt K. Solid-phase synthesis of moleculary imprinted polymer nanolabels: Affinity tools for cellular bioimaging of glycans. Scientific Reports2019, 9,3923.
 

Medina Rangel P., Moroni E., Merlier F., Gheber L., Vago R., Tse Sum Bui B., Haupt K. Chemical Antibody Mimics Inhibit Cadherin-Mediated Cell-Cell Adhesion: A Promising Strategy for Cancer Therapy. Angewandte Chemie2019, In press ,.
 

Alejandra MIER

PhD student UTC

Research

Member of the theme “Biomimicry and Biomolecular Diversity”.

PhD project: “Molecularly imprinted polymer nanocomposites as antibody mimics for cancer cell recognition and theranostics” under the supervision of B. Tse-Sum-Bui and K. Haupt.
Skills

  • Technical skills in biology, cell engineering (cell culture, cytotoxicity assays, ELISA, etc), microscopy (epifluorescence), microfluidics, analytical methods, polymer chemistry and nanoparticles characterization.
  • Languages: Spanish (native), English (fluent), French (fluent)

 

Roles and responsabilities

Administrative management of the MIP group.
General information

  • Bachelor degree in Biochemical Engineering, Autonomous University of Aguascalientes (Mexico)
  • Master degree in Biological Engineering, University of Technology of Compiègne (France)
  • PhD student in University of Technology of Compiègne (France)

 

Personal interests 

Travel

 

Main publications

Articles

Mier A., Nestora S., Medina Rangel P., Rossez Y., Haupt K., Tse Sum Bui B. Cytocompatibility of Moleculary Imprinted Polymers for Deodorants : Evaluation on Human Keratinocytes and Axillary-Hosted Bacteria . ACS Appl. Mater. Interfaces 2019, 2 ,3439-3447    ABSTRACT: https://doi.org/10.1021/acsabm.9b00388

Ernesto PARULI III

PhD student

Research

Member of the theme “Biomimicry and Biomolecular Diversity”.

PhD project: “Direct writing of 3D MIP micro and nanosensors by two photon stereolithography” under the supervision of C. Gonzato and K. Haupt.

Novel click chemistry for the synthesis of molecularly imprinted polymers (MIPs); two-photon stereolithography for the direct writing of 3D molecularly imprinted polymers (MIPs)

 

Skills

Chemical sensors and biosensors; analytical chemistry; polymer chemistry; use of Nanoscribe Photonic Professional (GT) 3D printer; work in a radioactivity laboratory; UV-Vis; fluorescence; infrared spectroscopies

General information

  • Bachelor of Science in Chemistry, University of Santo Tomas (Philippines)
  • Bachelor thesis: “Chitosan/citric acid-based piezoelectric sensor for trimethylamine”
  • Master of Science in Chemistry, University of Santo Tomas (Philippines)
  • Master thesis: “Aptamer-coupled quartz crystal as histamine sensor”
  • PhD student, Université de Technologie de Compiègne (France)
  • PhD thesis: “Direct writing of 3D MIP micro and nanosensors by two photon stereolithography”

 

Personal interests

Music, reading, learning languages, badminton

Nely RODRIGUEZ

PhD student UPJV

Research

Member of the theme “Plant Metabolism and Bioresources”.

PhD project: Anti-fungal properties of natural amphiphiles as viewed by molecular dynamics simulations (under the supervision of S. Buchoux).
Skills

Biophysics, computing and molecular dynamics.
General information

  • Licence & M1: Physics, Murcia University (Spain).
  • M2: Biological systems and physical concepts, UPMC Paris (France).
  • PhD in biophysics:  UPJV, Amiens (France).

 

Personal interests

Sport, nature.

Nicolas FAVELIN

PhD student UTC

Research

Member of the theme “Biomimicry and Biomolecular Diversity”

PhD project: “Selection and formulation of molecules to fight against Xylella fastidiosa” under the supervision of S. Octave and B. Bihan-Avalle.

 

Skills

Technical skills in plant biology (hydroponic plant growth), molecular biology (PCR, DNA cloning, DNA and protein analysis, MP-AES), microbiology (bacteria and yeast growth, recombinant protein production), genetics, bio-informatics (transcriptomic and genomic analysis), statistics and general lab experimentations.

Languages: French (native), English (fluent), Spanish (basic).

General information

Graduated from Ecole de Biologie Industrielle (EBI), Cergy Pontoise (France)

Specialty in Research and Application

Biology engineer diploma

Bachelor in Biochemistry and Cellular Biology,

UFR Sciences et Techniques, University of Cergy Pontoise, France

Currently PHD student in University of Technology of Compiègne (France)

Personal interests

Music, tennis, international travels

Tiffany AUROY

PhD student UTC

Research

Member of the theme « Biomimicry and Biomolecular Diversity »

Synthesis of nanoparticles to target gram negative bacterias and drug release.

Subject: « Molecular imprinted polymers for the vectorization and the stabilization of antimicrobial peptides : new approaches to combat antibiotic resistance » under the supervision of K. Haupt and B. Bihan-Avalle

Skills

Organic synthesis

Molecular purification and analysis : GC, RMN, liquid chromatography

Production of proteins (PCR,cell culture, electrophoresis, purification) by recombinant plasmid,.

Biocatalysis (enzypme activity assays, reactions of bioconversion)

General information

Bachelor licence degree in Biochemical and Biopharmaceutical Chemistry, Aix-Marseille University (France)

Master degree in Chemistry speciality « Chemistry of Life », Aix-Marseille University (France)
Academic research internship (Organic synthesis, Biocatalysis), Molecular Sciences Institute of Marseille (France)

PhD in Biology, Biochemistry and Cell Engineering, University of Picardie Jules Verne and University of Technology of Compiègne (France)

Personal interests

Sport, Sophrology, Music

Meihua GONG

PhD student UTC

Research

Member of the theme “Biomimicry and Biomolecular Diversity”.

PhD project: “A new tool to purify methylated peptide from bacteria in order to study bacterial mechanosensing” under the supervision of S. Padiolleau and Y. Rossez.

Skills

  • Technical skills: Cell culture, HPLC with fluorescence and ultraviolet detection, Gas chromatography, GC-MS, Molecular cloning, Protein expression and purification, Microbial fermentation.
  • Languages: Chinese (native), English (fluent), French (basic)

General information

  • 09/2012-06/2016: Bachelor degree in Biological Engineering, Huaibei Normal University (China)
  • 09/2016-06/2019: Master degree in Biochemical Engineering, Zhejiang University of Technology (China)
  • 12/2019-present: PhD student, UMR 7025 CNRS Enzyme and Cell Engineering, University of Technology of Compiègne (France)

Personal interests

swimming, music, reading, badminton

Ye TAO

PhD student UTC

Research

Member of the them “Biomimicry and Biomolecular Diversity”.

My PhD project of Y. Tao aims to develop a new strategy of biofilm degradation of P. aeruginosa bacteria by immobilizing a MIP targeting a DNase epitope under the supervision of L. Duma and Y. Rossez.
 

Skills

Molecular imprinting technology, HPLC, Cell culture.

Solid-phase synthesis of molecularly imprinted polymer nanoparticles for biofilm recognition.
 

General information

  • 09/2011-07/2015 : Ji Lin Business And Technology College Food Engineering; Major: Food Science and Engineering; Degree: Bachelor of Engineering
  • 09/2015-06/2018: Wuhan Polytechnic University; Major: Food Science and Engineering; Research direction: Grain, Oils and Vegetable Protein Engineering
  • 09/2018-present: Université de Technologie de Compiègne, UMR 7025 CNRS Enzyme and Cell Engineering

 

Personal interests

Basketball, swimming, music, skiing, sleeping